1 EPR based distance measurement in Cu - porphyrin - DNA

نویسندگان

  • ThaoNguyen Nguyen
  • Pär Håkansson
  • Ruth Edge
  • David Collison
  • Bernard A. Goodman
  • Jonathan R. Burns
  • Eugen Stulz
چکیده

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منابع مشابه

Design and Synthesis of a Multi Cu(II)-porphyrin Array

A new class of porphyrin array was synthesized. The Cu(II) porphyrin-PAMAM-Cu(II) porphyrin was obtained in good yields. The EPR studies showed that all porphyrins obtained have signals of a copper complex with planar geometry, and no variation in the tetrahedral distortion of the porphyrin ring was observed. The UV-vis and emission studies showed that the intensity of the signal increased due ...

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Nanorings with copper(ii) and zinc(ii) centers: forcing copper porphyrins to bind axial ligands in heterometallated oligomers† †Electronic supplementary information (ESI) available: Synthesis and characterization of new compounds, UV-vis-NIR titrations and binding data for reference compounds and for the formation of linear oligomer complexes, error analysis and calculation of statistical factors. See DOI: 10.1039/c6sc01809b Click here for additional data file.

The affinity of copper(II) porphyrins for pyridine ligands is extremely weak, but oligo-pyridine templates can be used to direct the synthesis of Cu-containing cyclic porphyrin oligomers when they also have Zn centers. We report the synthesis of two heterometallated nanorings: a six-porphyrin ring prepared from a Zn/Cu/Zn linear trimer and a ten-porphyrin ring prepared from a Zn/Zn/Cu/Zn/Zn pen...

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DNA groove binding of an asymmetric cationic porphyrin and its Cu(II) complex: Resolved by spectroscopic, viscometric and molecular docking studies

In the present study, the interaction between water-soluble cationic asymmetric porphyrin, 5-(1-Hexadecyl pyridinium-4-yl)-10, 15, 20-tris (1-Butyl pyridinium-4-yl) Porphyrin Chloride, and its copper (II) derivative with calf thymus DNA (CT-DNA) were studied by means of spectroscopic techniques, viscosity measurements and molecular docking. The monitoring of the changes in visible absorbance sp...

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The influence of G-quadruplex structure on DNA-based asymmetric catalysis using the G-quadruplex-bound cationic porphyrin TMPyP4·Cu.

The DNA G-quadruplex-binding porphyrin TMPyP4·Cu was found to form efficient hybrid catalysts for DNA-based asymmetric catalysis when bound to DNA G-quadruplexes. Nucleobase substitution experiments using human telomere-derived G-quadruplex sequences suggest binding of the porphyrin on the 3'-face.

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Nanorings with copper(ii) and zinc(ii) centers: forcing copper porphyrins to bind axial ligands in heterometallated oligomers.

The affinity of copper(ii) porphyrins for pyridine ligands is extremely weak, but oligo-pyridine templates can be used to direct the synthesis of Cu-containing cyclic porphyrin oligomers when they also have Zn centers. We report the synthesis of two heterometallated nanorings: a six-porphyrin ring prepared from a Zn/Cu/Zn linear trimer and a ten-porphyrin ring prepared from a Zn/Zn/Cu/Zn/Zn pen...

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تاریخ انتشار 2014